$75 Cheap flights from McGhee Tyson to San Francisco Intl. (TYS to SFO)

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Find The Best Dates To Fly from McGhee Tyson to San Francisco Intl.

Amazing TYS to SFO Flight Deals

The cheapest flights to San Francisco Intl. found within the past 7 days were $138 round trip and $75 one way. Prices and availability subject to change. Additional terms may apply.

Thu, Jan 16 - Wed, Jan 22
TYS
Knoxville
SFO
San Francisco
$138 Roundtrip, found 10 hours ago
$138
Roundtrip
found 10 hours ago
Select Frontier Airlines flight, departing Thu, Jan 16 from Knoxville to San Francisco, returning Wed, Jan 22, priced at $138 found 10 hours ago
Thu, Jan 16 - Sun, Jan 19
TYS
Knoxville
SFO
San Francisco
$158 Roundtrip, found 10 hours ago
$158
Roundtrip
found 10 hours ago
Select Frontier Airlines flight, departing Thu, Jan 16 from Knoxville to San Francisco, returning Sun, Jan 19, priced at $158 found 10 hours ago
Thu, Jan 16 - Sun, Feb 2
TYS
Knoxville
SFO
San Francisco
$178 Roundtrip, found 4 days ago
$178
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Jan 16 from Knoxville to San Francisco, returning Sun, Feb 2, priced at $178 found 4 days ago
Sun, Jan 12 - Sun, Feb 2
TYS
Knoxville
SFO
San Francisco
$198 Roundtrip, found 4 days ago
$198
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sun, Jan 12 from Knoxville to San Francisco, returning Sun, Feb 2, priced at $198 found 4 days ago
Sun, Jan 12 - Thu, Jan 16
TYS
Knoxville
SFO
San Francisco
$238 Roundtrip, found 10 hours ago
$238
Roundtrip
found 10 hours ago
Select Frontier Airlines flight, departing Sun, Jan 12 from Knoxville to San Francisco, returning Thu, Jan 16, priced at $238 found 10 hours ago
Wed, Nov 27 - Thu, Dec 12
TYS
Knoxville
SFO
San Francisco
$246 Roundtrip, found 5 days ago
$246
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Wed, Nov 27 from Knoxville to San Francisco, returning Thu, Dec 12, priced at $246 found 5 days ago
Sun, Jan 19 - Thu, Feb 6
TYS
Knoxville
SFO
San Francisco
$254 Roundtrip, found 4 days ago
$254
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sun, Jan 19 from Knoxville to San Francisco, returning Thu, Feb 6, priced at $254 found 4 days ago
Thu, Dec 5 - Sun, Dec 15
TYS
Knoxville
SFO
San Francisco
$258 Roundtrip, found 18 hours ago
$258
Roundtrip
found 18 hours ago
Select Frontier Airlines flight, departing Thu, Dec 5 from Knoxville to San Francisco, returning Sun, Dec 15, priced at $258 found 18 hours ago
Sun, Dec 8 - Thu, Dec 12
TYS
Knoxville
SFO
San Francisco
$288 Roundtrip, found 7 hours ago
$288
Roundtrip
found 7 hours ago
Select Frontier Airlines flight, departing Sun, Dec 8 from Knoxville to San Francisco, returning Thu, Dec 12, priced at $288 found 7 hours ago
Sun, Dec 8 - Sun, Dec 15
TYS
Knoxville
SFO
San Francisco
$294 Roundtrip, found 1 day ago
$294
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Dec 8 from Knoxville to San Francisco, returning Sun, Dec 15, priced at $294 found 1 day ago

Best San Francisco Intl. Flight and Hotel Packages

San Francisco Intl. flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
Hotel Zelos San Francisco

Hotel Zelos San Francisco

4 out of 5
per person
Jan 16 - Jan 20
found 20 hours ago
Roundtrip non-stop flight included
Knoxville (TYS) to San Francisco (SFO)
Hotel E

Hotel E

3.5 out of 5
per person
Jan 16 - Jan 20
found 1 day ago
Roundtrip non-stop flight included
Knoxville (TYS) to San Francisco (SFO)
Cavallo Point

Cavallo Point

4.5 out of 5
Save 100% on your flight
per person
Jan 9 - Jan 12
just found
Roundtrip non-stop flight included
Knoxville (TYS) to San Francisco (SFO)
Hotel Zetta San Francisco

Hotel Zetta San Francisco

4 out of 5
per person
Jan 16 - Jan 20
found 20 hours ago
Roundtrip non-stop flight included
Knoxville (TYS) to San Francisco (SFO)
The Westin Palo Alto

The Westin Palo Alto

4 out of 5
Save 100% on your flight
per person
Jan 9 - Jan 12
just found
Roundtrip non-stop flight included
Knoxville (TYS) to San Francisco (SFO)
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Frequently asked questions

Can I catch a flight from McGhee Tyson Airport (TYS) to San Francisco Intl. Airport (SFO) right now?
Make sure you go to our Covid-19 Travel Advisor to learn if there are any present travel advice reports and quarantine requirements in place in SFO when flying in from McGhee Tyson Airport (TYS).
Are there direct flights from TYS to San Francisco Airport?
United Airlines, American Airlines and Delta will get you to San Francisco from Louisville with just one stopover. Unfortunately, there are no direct flights between TYS and SFO just yet.
If I am not able to travel due to COVID-19, can I change my booking to a later date?
For more info about changing your flight to SFO, please visit our Customer Service Portal.
How long is the flight from Knoxville Airport to SFO?
It takes approximately 6 hours and 43 minutes to journey from Knoxville Airport to San Francisco Airport. You’ll be in the air for a while, so keep yourself amused with a film or get stuck into the airway’s magazines.
What is the flight distance from Knoxville Airport to SFO?
There’s a flight distance of 2,100 mi separating TYS and San Francisco Airport. This is classified as a medium-haul flight. There’ll be plenty of time to watch the in-flight entertainment and squeeze in some sleep if you’re feeling weary.
What airlines fly from Knoxville Airport to San Francisco Intl. Airport (SFO)?
No airlines are currently offering direct flights between Knoxville Airport and San Francisco Airport. Save time and avoid annoying stopovers by researching the best routes in advance.
What airlines have practices regarding COVID-19 in place and use social distancing?
From the moment you enter the departure terminal to when you leave the arrivals terminal, if you’re flying with United Airlines, Alaska Airlines or Delta you can be sure that COVID-19 measures and social distancing rules have been adhered to. Many airlines have introduced capped capacity flights and keeping the middle seat empty.
What is the best day to buy a plane ticket?
This just in! Airfares offered on Thursdays tend to be the cheapest, according to flight demand on Travelocity in 2021. Tuesday and Wednesday prices are also good, but you may want to prepare your budget if booking during the weekend, as data shows that is when prices are generally at their highest.
What are the cheapest days to fly?
Frequent travelers may already know this, but earlier in the week can be the cheapest time to fly. In 2021, flights departing on a Monday were generally the cheapest of the week, whereas you may pay a premium for weekend flights when demand is usually high. On average, tickets were most expensive for Saturday departures, so if you need to fly out on a weekend, you might look for deals ahead of time.
How far in advance can you book a flight?
Trying to figure out how early you should book your flight? It’s possible to start comparing international airfares on Travelocity up to 12 months in advance. However, it does depend on the carrier as not all airlines release their prices that far out. According to our 2021 flight demand trends, last minute planners can still bag a bargain with some of the cheapest fares appearing 0-2 weeks prior to their travel dates.*According to flight demand on Travelocity.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

 

Traveling From
McGhee Tyson
Traveling To
San Francisco Intl.
Shortest Flight Time
 hours mins
Earliest Departure Time
Latest Departure Time
Lowest Flight Price
$138

Route Info

Flight path for flights from McGhee Tyson Airport to San Francisco International Airport


Origin:
TYS - McGhee Tyson Airport
Destination:
SFO - San Francisco International Airport
Distance:
2,481.00 miles


Airlines & Aircraft Used on TYS to SFO Flight Routes


Airline Carrier
Aircraft
American Airlines
Boeing 737-700 pax
American Airlines
Boeing 737-800 pax
American Airlines
Boeing 757 all pax models

Discover our best flights from Knoxville TYS to San Francisco SFO. 

With 20 airlines to choose from on Travelocity, you can easily find the best option for you. Use our filters to sort by price, compare airlines, and find the most convenient flight times. 

 

Find our best return flights from Knoxville TYS to San Francisco SFO at the right price  

Airfares to San Francisco SFO from Knoxville TYS currently cost between $138 and $294. It’s usually cheaper to book a round trip than two separate one-way flights. Prices and availability subject to change. Additional terms may apply. 

 

Book one-way flights from Knoxville TYS to San Francisco SFO 

If you want to be flexible about when you return, or keep your travel options open ended, a one-way flight could be just the ticket! You’ll find one-way airfares from Knoxville TYS to San Francisco SFO on Travelocity starting at $75. Prices and availability subject to change. Additional terms may apply. 

 

Get to San Francisco SFO from Knoxville TYS quicker with direct flights. 

Get to San Francisco faster, without the hassle of changing planes and moving baggage, by booking a direct flight. Expect your direct flight to SFO from TYS to take around hour(s) min(s).  

 

Find our cheapest airfares for flights from Knoxville TYS to San Francisco SFO

Find cheap flight deals by using our search filters to sort results starting with the lowest price airfares to SFO from TYS. Our Price Match Promise means if you find a lower rate on Travelocity.com or on another US-based website within 24 hours of booking, we’ll credit or refund the difference.  

 

Get our best airfare deals for your flight from Knoxville TYS to San Francisco SFO today 

If you’re flexible about when you travel, January is usually the cheapest month to fly from Knoxville TYS to San Francisco SFO. If you need to be more specific, search by date and arrival and departure times.Then, compare prices across different airlines, and sort results by lowest price first. 

 

Book flexible airline tickets for flights to San Francisco SFO from Knoxville TYS 

Some airlines let you change your travel dates without charging a fee. Use our ‘no change fee’ filter to see which flights to SFO from TYS have this option.  

 

Travel with confidence when you book flights to San Francisco SFO from Knoxville TYS with Travelocity 

We’ve secured fantastic deals with all the main airline carriers and it’s easy to compare, choose, and book with Travelocity. With 24/7 customer service and our free 'App', we’ll always keep you moving. 

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.