American Airlines Flight AA5221 Deals & Information (2024/2025)

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

American Airlines Flight 5221 Route Deals From $185

The cheapest prices found with in the last 7 days for return flights were $376 and $185 for one-way flights to Ronald Reagan Washington National for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

What route does flight number AA5221 take?
AA5221 is used on multiple routes. More commonly, AA5221 flies straight from Daytona Beach, FL Airport (DAB-Daytona Beach Intl.) to Charlotte, NC Airport (CLT-Charlotte-Douglas Intl.). If you’ve booked a seat on this route, you’ll be up above the clouds for around 1 hour and 48 minutes.
How often is AA5221 on time?
If you’re traveling with American Airlines flight number AA5221 from DAB to Charlotte, NC Airport (CLT-Charlotte-Douglas Intl.), it’s a relief knowing that their planes run according to schedule 92% of the time. In the rare event that a flight is running behind schedule, it should only be delayed by around 10 minutes. Thanks to this airline’s top standards, this flight has a 3.9-star rating.
What kind of plane is on flight number AA5221?
If you have a seat on flight AA5221 from Daytona Beach Intl. Airport (DAB) to Charlotte Airport, you’ll likely be aboard the Bombardier CRJ900. This flight number serves a number of routes, but this is the most common one.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA5221 flight with Travelocity, please visit our Customer Service Portal.