American Airlines Flight AA5221 Deals & Information (2025/2026)

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American Airlines Flight 5221 Route Deals From $165

The cheapest prices found with in the last 7 days for return flights were $329 and $165 for one-way flights to Dane County Regional for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Aug 13 - Tue, Aug 19
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$329 Roundtrip, found 6 days ago
$329
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Aug 13 from Ronald Reagan Washington National to Dane County Regional, returning Tue, Aug 19, priced at $329 found 6 days ago
Wed, May 21 - Sun, May 25
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$335 Roundtrip, found 2 days ago
$335
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, May 21 from Ronald Reagan Washington National to Dane County Regional, returning Sun, May 25, priced at $335 found 2 days ago
Tue, Jun 17 - Wed, Jun 25
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$341 Roundtrip, found 2 days ago
$341
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Jun 17 from Ronald Reagan Washington National to Dane County Regional, returning Wed, Jun 25, priced at $341 found 2 days ago
Tue, Jun 17 - Wed, Jun 25
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$350 Roundtrip, found 2 days ago
$350
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Jun 17 from Ronald Reagan Washington National to Dane County Regional, returning Wed, Jun 25, priced at $350 found 2 days ago

Frequently asked questions

What route does flight number AA5221 take?
AA5221 is used on multiple routes. More commonly, AA5221 flies straight from Daytona Beach, FL Airport (DAB-Daytona Beach Intl.) to Charlotte, NC Airport (CLT-Charlotte-Douglas Intl.). If you’ve booked a seat on this route, you’ll be up above the clouds for around 1 hour and 48 minutes.
How often is AA5221 on time?
If you’re traveling with American Airlines flight number AA5221 from DAB to Charlotte, NC Airport (CLT-Charlotte-Douglas Intl.), it’s a relief knowing that their planes run according to schedule 92% of the time. In the rare event that a flight is running behind schedule, it should only be delayed by around 10 minutes. Thanks to this airline’s top standards, this flight has a 3.9-star rating.
What kind of plane is on flight number AA5221?
If you have a seat on flight AA5221 from Daytona Beach Intl. Airport (DAB) to Charlotte Airport, you’ll likely be aboard the Bombardier CRJ900. This flight number serves a number of routes, but this is the most common one.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA5221 flight with Travelocity, please visit our Customer Service Portal.