$136 Cheap Delta flights from Des Moines to Buffalo (DSM to BUF)

Find The Best Day To Fly from Des Moines to Buffalo

Amazing Delta DSM to BUF Flight Deals

The cheapest flights to Buffalo Niagara Intl. found within the past 7 days were $297 round trip and $136 one way. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Can I catch a flight from Des Moines Intl. Airport to Buffalo Niagara Intl. Airport (BUF) right now?
For any present Buffalo Niagara International Airport travel advice and quarantine requirements, go to our Covid-19 Travel Advisor. Check before you arrange your flight, so you don’t get caught up en route.
What terminal is Delta Air Lines at DSM?
As soon as you receive your ticket for your Delta Air Lines flight from Des Moines Intl. Airport (DSM) to BUF, see if the terminal details are written on it. If not, ask your air carrier. They’ll be able to tell you where you’ll be flying in and out of.
Are there Delta Air Lines non-stop flights from DSM to BUF?
If you’re traveling with Delta Air Lines from DSM to Buffalo Niagara International Airport, you’ll need to make a stopover. While waiting for your connection, take the chance to grab a refreshment or check out the airport shops.
How long is a Delta Air Lines flight from DSM to BUF?
Depending on good weather and no delays, your Delta Air Lines flight from DSM to BUF will take about 4 hours and 10 minutes. That means you’ve got enough time to eat a meal, get some shut-eye and go over your travel schedule before you land.
How many direct and indirect flights does Delta Air Lines fly from DSM to BUF?
If you want to book a jaunt from DSM to BUF, you can select from around 3 Delta Air Lines flights daily.
If I am not able to travel due to COVID-19, can I change my booking to a later date?
For more info about changing your flight to Buffalo Niagara International Airport, please visit our Customer Service Portal.
What is the best day to buy a plane ticket?
This just in! Airfares offered on Thursdays tend to be the cheapest, according to flight demand on Travelocity in 2021. Tuesday and Wednesday prices are also good, but you may want to prepare your budget if booking during the weekend, as data shows that is when prices are generally at their highest.
What are the cheapest days to fly?
Frequent travelers may already know this, but earlier in the week can be the cheapest time to fly. In 2021, flights departing on a Monday were generally the cheapest of the week, whereas you may pay a premium for weekend flights when demand is usually high. On average, tickets were most expensive for Saturday departures, so if you need to fly out on a weekend, you might look for deals ahead of time.
How far in advance can you book a flight?
Trying to figure out how early you should book your flight? It’s possible to start comparing international airfares on Travelocity up to 12 months in advance. However, it does depend on the carrier as not all airlines release their prices that far out. According to our 2021 flight demand trends, last minute planners can still bag a bargain with some of the cheapest fares appearing 0-2 weeks prior to their travel dates.*According to flight demand on Travelocity.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Discover our best Delta flight from Des Moines DSM to Buffalo BUF 

To find the best deals on flights to Des Moines from Buffalo with Delta, just enter your travel dates, filter by Delta, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.  

 

Return flights from Des Moines DSM to Buffalo BUF with Delta 

If you’re planning a round trip, booking return flights with Delta is usually the most cost-effective option. With airfares ranging from $297 to $365, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply. 

 

Book one-way Delta flights from Des Moines DSM to Buffalo BUF 

A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way Delta flight from Des Moines to Buffalo costs from $136. Prices and availability subject to change. Additional terms may apply. 

 

The easy way to find cheap flights to Buffalo BUF from  Des Moines DSM with Delta 

To find a cheap Delta flight from Des Moines DSM to Buffalo BUF, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference. 

 

How to find our best airfare deals on Delta flights from Des Moines DSM to Buffalo BUF 

If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as September, or if you book a flight with a stopover. 

 

Find nonstop flights from Des Moines DSM to Buffalo BUF with Delta 

If you’re keen to be on Buffalo soil fast, don’t waste time with a stopover—filter your search results to show direct Delta flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it. 

 

Flexible airline tickets for Delta flights from Des Moines DSM to Buffalo BUF 

Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.  

 

There are a lot of reasons to book your flights to Buffalo BUF from  Des Moines DSM with Delta on Travelocity 

At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.

Delta Airports
Hop on a(n) Delta flight today by flying to many destinations out of these domestic and international airports:
Airport code
Country
Airport name
Number of flights
ATLUSAHartsfield-Jackson Atlanta Intl.252
DTWUSADetroit Metropolitan Wayne County156
MSPUSAMinneapolis - St. Paul Intl.131
SLCUSASalt Lake City Intl.116
SEAUSASeattle - Tacoma Intl.57
LAXUSALos Angeles Intl.41
AMSNLDSchiphol31
YYCCANCalgary Intl.26
YYZCANPearson Intl.24
JFKUSAJohn F. Kennedy Intl.23

Travelers ❤️ these 🏨 after their flight to Buffalo

Buffalo Airport Hotel
Buffalo Airport Hotel
3 out of 5
4600 Genesee St, Buffalo, NY
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8/10 Very Good! (2,447 reviews)
"Nice hotel! Great restaurant! Close to airport parking!"

Reviewed on Apr 19, 2025

Buffalo Airport Hotel
Sleep Inn & Suites Buffalo Airport
Sleep Inn & Suites Buffalo Airport
2.5 out of 5
100 Holtz Dr, Buffalo, NY
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free self parking, and a free airport shuttle. Traveling on business? Take advantage ...
8/10 Very Good! (1,536 reviews)
"The manager was especially good, Nyesha is a class act!!"

Reviewed on Apr 24, 2025

Sleep Inn & Suites Buffalo Airport
M Hotel Buffalo
M Hotel Buffalo
3.5 out of 5
2040 Walden Ave, Buffalo, NY
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport ...
7/10 Good! (1,327 reviews)
"Loved this hotel for my family especially the pool"

Reviewed on Apr 21, 2025

M Hotel Buffalo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.