$146 Cheap American Airlines flights from Knoxville to Gainesville (TYS to GNV)

Find The Best Day To Fly from Knoxville to Gainesville

Amazing American Airlines TYS to GNV Flight Deals

The cheapest flights to Gainesville Regional found within the past 7 days were $462 round trip and $146 one way. Prices and availability subject to change. Additional terms may apply.

GNV From TYS Economy Coach Packages on Similar Airlines

Price found within the past 48 hours. Click for updated prices.
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Discover our best American Airlines flight from Knoxville TYS to Gainesville GNV 

To find the best deals on flights to Knoxville from Gainesville with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.  

 

Return flights from Knoxville TYS to Gainesville GNV with American Airlines 

If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $462 to $562, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply. 

 

Book one-way American Airlines flights from Knoxville TYS to Gainesville GNV 

A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Knoxville to Gainesville costs from $146. Prices and availability subject to change. Additional terms may apply. 

 

The easy way to find cheap flights to Gainesville GNV from  Knoxville TYS with American Airlines 

To find a cheap American Airlines flight from Knoxville TYS to Gainesville GNV, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference. 

 

How to find our best airfare deals on American Airlines flights from Knoxville TYS to Gainesville GNV 

If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as November, or if you book a flight with a stopover. 

 

Find nonstop flights from Knoxville TYS to Gainesville GNV with American Airlines 

If you’re keen to be on Gainesville soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it. 

 

Flexible airline tickets for American Airlines flights from Knoxville TYS to Gainesville GNV 

Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.  

 

There are a lot of reasons to book your flights to Gainesville GNV from  Knoxville TYS with American Airlines on Travelocity 

At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.

American Airlines Airports
Hop on a(n) American Airlines flight today by flying to many destinations out of these domestic and international airports:
Airport code
Country
Airport name
Number of flights
DFWUSADallas-Fort Worth Intl.599
CLTUSACharlotte-Douglas Intl.536
ORDUSAO'Hare Intl.317
PHLUSAPhiladelphia Intl.247
MIAUSAMiami Intl.193
DCAUSARonald Reagan Washington National152
PHXUSASky Harbor Intl.141
LAXUSALos Angeles Intl.81
LGAUSALaGuardia72
BOSUSALogan Intl.57

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3 out of 5
212 SE 1ST STREET,, Gainesville, FL
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (855 reviews)
Great location
"Hotel is modern and beds are comfortable. It’s a short distance to the UF campus. Has restaurants next to it including an ice cream shop. The pool area is nice too. The street crowds can be noisy but hotel provided ear plugs in each room. We didn’t find the noise to be distracting."

Reviewed on Apr 20, 2025

Hyatt Place Gainesville Downtown
4 Bedroom Single Family home 5 mins to University!
4 Bedroom Single Family home 5 mins to University!
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An outdoor pool is featured at this vacation home, along with laundry facilities.
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Reviewed on Mar 18, 2025

4 Bedroom Single Family home 5 mins to University!
Sweetwater Branch Inn
Sweetwater Branch Inn
3.5 out of 5
625 East University Avenue, Gainesville, FL
This bed & breakfast features an outdoor pool and a hot tub. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. ...
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Sweetwater Branch Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.