South Carolina Midlands , SC Pet Friendly Hotels

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Top South Carolina Midlands Pet Friendly Hotels

Hampton Inn Columbia I-26/Harbison Blvd.

Hampton Inn Columbia I-26/Harbison Blvd.

101 Woodcross Dr, Columbia, SC
Fully refundableReserve now, pay when you stay
The price is $113 per night from May 18 to May 19
$113
includes taxes & fees
$101 per night
May 18 - May 19
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
9/10 Wonderful! (1,000 reviews)
"Fridge was making a loud ringing noise. Everything else was great."

Reviewed on Apr 21, 2025

Hampton Inn Columbia I-26/Harbison Blvd.
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

139 Bradford Blvd, Santee, SC
Fully refundable
The price is $150 per night from May 26 to May 27
$150
includes taxes & fees
$135 per night
May 26 - May 27
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
8/10 Very Good! (877 reviews)
Nice place to stay
"I had booked this hotel and discovered it was a tad beyond our turn off. However we were not disappointed! And it turned out it wasn’t that much out of our way. After traveling all day this looked like a newly built hotel. So the little newly added conveniences were appreciated. I kept thinking “ ..."

Reviewed on Apr 24, 2025

Holiday Inn Santee by IHG
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

2123 W Lucas St, Florence, SC
Fully refundableReserve now, pay when you stay
The price is $109 per night from May 18 to May 19
$109
includes taxes & fees
$98 per night
May 18 - May 19
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
7.8/10 Good! (1,635 reviews)
"Quick check-in"

Reviewed on Apr 24, 2025

La Quinta Inn & Suites by Wyndham Florence
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Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr, Florence, SC
Fully refundableReserve now, pay when you stay
The price is $93 per night from May 26 to May 27
$93
includes taxes & fees
$83 per night
May 26 - May 27
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
7.8/10 Good! (1,198 reviews)
"Very comfortable bed"

Reviewed on Apr 22, 2025

Quality Inn & Suites Florence Civic Center
Inn at Orangeburg

Inn at Orangeburg

731 Citadel Road, Orangeburg, SC
Fully refundableReserve now, pay when you stay
The price is $131 per night from May 4 to May 5
$131
includes taxes & fees
$118 per night
May 4 - May 5
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
7.6/10 Good! (1,002 reviews)
"I enjoyed my hotel stay. The room was remodeled and new bed and linens were really comfortable. I would stay there again. I wish the breakfast was available but it wasn't. I overall it was a good place to stay"

Reviewed on Apr 24, 2025

Inn at Orangeburg
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

7333 Garners Ferry Rd, Columbia, SC
Fully refundableReserve now, pay when you stay
The price is $94 per night from May 4 to May 5
$94
includes taxes & fees
$84 per night
May 4 - May 5
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
7.4/10 Good! (1,005 reviews)
"The hotel lobby area is really nice and clean and comfortable."

Reviewed on Apr 25, 2025

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2690 David H McLeod Boulevard, Florence, SC
Fully refundableReserve now, pay when you stay
The price is $63 per night from Apr 30 to May 1
$63
includes taxes & fees
$56 per night
Apr 30 - May 1
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
6.6/10 (1,001 reviews)
"Clean rooms, Peaceful area , great room service, good coffee"

Reviewed on Apr 13, 2025

Red Roof Inn Florence - Civic Center
Baymont Inn & Suites Florence by Wyndham

Baymont Inn & Suites Florence by Wyndham

1826 W Lucas Street, Florence, SC
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self ...
5.6/10 (1,000 reviews)
"Still in Renovation mode"

Reviewed on Sep 3, 2024

Get rates
Baymont Inn & Suites Florence by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

It’s hard to leave for a trip when the last image you have is of your four-legged best friend staring out the living-room window with those sad eyes as you drive away. You don’t have to leave Spot behind any longer, he can finally join you on your adventures.

Turn your trip into a family getaway by booking a stay at one of the pet-friendly hotels in South Carolina Midlands for you and your furry kids. No more sending them to pet hotels or leaving them home alone to run amok in the house. South Carolina Midlands pet-friendly hotels are perfect for weekend escapes with your pooch, kitty, bird, or fish. These accommodations not only welcome your pets, but they offer many services to help make your stay more relaxing. Things like on-site grooming and complimentary dog walking are some of the amenities provided. In most cases, you’ll also be near outdoor spaces like dog parks if you both need some exercise, as well as pet-friendly restaurants.

Don’t ever feel guilty about leaving your beloved Maximus behind on a trip again. Travelocity wants to help the both of you enjoy a wonderful vacation together. Search our extensive inventory of the best pet-friendly hotels in South Carolina Midlands and book your stay now.

Seize your some day

South Carolina Midlands hotels essential information

Accommodation
2,840 hotels
Lowest Price
$63
Highest Price
$150
Popular hotels
La Quinta Inn & Suites by Wyndham Florence, La Quinta Inn by Wyndham Columbia SE / Fort Jackson, Hampton Inn Columbia I-26/Harbison Blvd., Inn at Orangeburg, Quality Inn & Suites Florence Civic Center, Holiday Inn Santee by IHG, Red Roof Inn Florence - Civic Center, Baymont Inn & Suites Florence by Wyndham

Recent South Carolina Midlands hotel reviews by fellow wanderers

La Quinta Inn by Wyndham Columbia NE/Fort Jackson

La Quinta Inn by Wyndham Columbia NE/Fort Jackson

5 out of 5
Posted 4 days ago
Travelocity Verified Review
"Great hotel in an area close to everything. Hotel was clean. "
A verified traveler stayed at La Quinta Inn by Wyndham Columbia NE/Fort Jackson
La Quinta Inn by Wyndham Columbia NE/Fort Jackson
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

5 out of 5
Posted 6 days ago
Travelocity Verified Review
"I were just passing through. I bought a motorcycle in Mississippi on Tuesday. I traveled to Atlanta and stayed for the night. Returned to further my trip back to Bowie Md. I reached South Carolina on the night and decided to rest there Wednesday Night. I resumed my destination Thursday evening after a family gathering and reached my home by 8 pm Thursday Night. "
A verified traveler stayed at Quality Inn & Suites Florence Civic Center
Quality Inn & Suites Florence Civic Center
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