Cheap flights from O'Hare Intl. to Vilo Acuna (ORD to CYO)

Discover our best flights from Chicago ORD to Cayo Largo CYO. 

With airlines to choose from on Travelocity, you can easily find the best option for you. Use our filters to sort by price, compare airlines, and find the most convenient flight times. 

Find our best return flights from Chicago ORD to Cayo Largo CYO at the right price  

Airfares to Cayo Largo CYO from Chicago ORD currently cost between and . It’s usually cheaper to book a round trip than two separate one-way flights. Prices and availability subject to change. Additional terms may apply. 

Book one-way flights from Chicago ORD to Cayo Largo CYO 

If you want to be flexible about when you return, or keep your travel options open ended, a one-way flight could be just the ticket! You’ll find one-way airfares from Chicago ORD to Cayo Largo CYO on Travelocity starting at . Prices and availability subject to change. Additional terms may apply. 

Get to Cayo Largo CYO from Chicago ORD quicker with direct flights. 

Get to Cayo Largo faster, without the hassle of changing planes and moving baggage, by booking a direct flight. Expect your direct flight to CYO from ORD to take around hour(s) min(s).  

Find our cheapest airfares for flights from Chicago ORD to Cayo Largo CYO

Find cheap flight deals by using our search filters to sort results starting with the lowest price airfares to CYO from ORD. Our Price Match Promise means if you find a lower rate on Travelocity.com or on another US-based website within 24 hours of booking, we’ll credit or refund the difference.  

Get our best airfare deals for your flight from Chicago ORD to Cayo Largo CYO today 

If you’re flexible about when you travel, is usually the cheapest month to fly from Chicago ORD to Cayo Largo CYO. If you need to be more specific, search by date and arrival and departure times.Then, compare prices across different airlines, and sort results by lowest price first. 

Book flexible airline tickets for flights to Cayo Largo CYO from Chicago ORD 

Some airlines let you change your travel dates without charging a fee. Use our ‘no change fee’ filter to see which flights to CYO from ORD have this option.  

Travel with confidence when you book flights to Cayo Largo CYO from Chicago ORD with Travelocity 

We’ve secured fantastic deals with all the main airline carriers and it’s easy to compare, choose, and book with Travelocity. With 24/7 customer service and our free 'App', we’ll always keep you moving.