$59 Cheap flights from Des Moines Intl. to San Diego Intl. (DSM to SAN)

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

Find The Best Dates To Fly from Des Moines Intl. to San Diego Intl.

Amazing DSM to SAN Flight Deals

The cheapest flights to San Diego Intl. found within the past 7 days were $138 round trip and $59 one way. Prices and availability subject to change. Additional terms may apply.

Best San Diego Intl. Flight and Hotel Packages

San Diego Intl. flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
Hampton Inn San Diego Del Mar
DoubleTree by Hilton Hotel San Diego - Mission Valley
Estancia La Jolla Hotel & Spa
Sheraton San Diego Hotel and Marina
 Hampton Inn & Suites San Diego Airport Liberty Station
Don't see what you're looking for?
See all available trips from Des Moines Intl. to San Diego Intl.
View all trips

Frequently asked questions

Can I catch a flight from DSM to San Diego Airport right now?
For information on any current SAN travel advice and quarantine requirements, visit our Covid-19 Travel Advisor. Check before you arrange your flight, so you don’t get caught out.
Are there direct flights from Des Moines Intl. Airport (DSM) to San Diego Airport?
Make a note of your connecting gate, because there are no direct flights between DSM and San Diego Intl. Airport (SAN). American Airlines, United Airlines and Alaska Airlines are some airlines that will get you to San Diego County with only one stopover.
If I am not able to travel due to COVID-19, can I change my booking to a later date?
For more info about changing your flight to San Diego Intl. Airport (SAN), please visit our Customer Service Portal.
How long is the flight from Des Moines Intl. Airport to San Diego Airport?
If you’re flying from Des Moines Intl. Airport to SAN, you can expect the trip to take about 5 hours and 9 minutes. If this sounds like more time than you anticipated, why not take advantage of it? Read up on your destination, organize some last-minute details and have a nap before the adventure begins.
What is the flight distance from DSM to San Diego Intl. Airport (SAN)?
Traveling 1,450 mi between DSM and DSM calls for a glass of bubbly and a few good movies. Lean back, pull a blanket over your lap and enjoy the flight.
What airlines fly from Des Moines Intl. Airport to San Diego Intl. Airport (SAN)?
Unfortunately, no airlines currently offer direct flights between Des Moines Intl. Airport and San Diego Intl. Airport (SAN). It’s in your best interest to plan well in advance to find the ideal price and route.
What airlines have practices regarding COVID-19 in place and use social distancing?
From the moment you enter the departure terminal to when you leave the arrivals terminal, if you’re flying with Southwest Airlines, Alaska Airlines or United Airlines you can be sure that COVID-19 measures and social distancing rules have been adhered to. Many airlines have introduced capped capacity flights and keeping the middle seat empty.
What is the best day to buy a plane ticket?
This just in! Airfares offered on Thursdays tend to be the cheapest, according to flight demand on Travelocity in 2021. Tuesday and Wednesday prices are also good, but you may want to prepare your budget if booking during the weekend, as data shows that is when prices are generally at their highest.
What are the cheapest days to fly?
Frequent travelers may already know this, but earlier in the week can be the cheapest time to fly. In 2021, flights departing on a Monday were generally the cheapest of the week, whereas you may pay a premium for weekend flights when demand is usually high. On average, tickets were most expensive for Saturday departures, so if you need to fly out on a weekend, you might look for deals ahead of time.
How far in advance can you book a flight?
Trying to figure out how early you should book your flight? It’s possible to start comparing international airfares on Travelocity up to 12 months in advance. However, it does depend on the carrier as not all airlines release their prices that far out. According to our 2021 flight demand trends, last minute planners can still bag a bargain with some of the cheapest fares appearing 0-2 weeks prior to their travel dates.*According to flight demand on Travelocity.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

 

Traveling From
Des Moines Intl.
Traveling To
San Diego Intl.
Shortest Flight Time
hours mins
Earliest Departure Time
Latest Departure Time
Lowest Flight Price
$138

Route Info

Flight path for flights from Des Moines International Airport to San Diego International Airport


Distance:
2,028.00 miles


Airlines & Aircraft Used on DSM to SAN Flight Routes


Airline Carrier
Aircraft
American Airlines
De Havilland Canada DHC-6 Twin Otter
American Airlines
Harbin Yunshuji Y12
United Airlines
Boeing 737-200 pax

Discover our best flights from Des Moines DSM to San Diego SAN. 

With 20 airlines to choose from on Travelocity, you can easily find the best option for you. Use our filters to sort by price, compare airlines, and find the most convenient flight times. 

 

Find our best return flights from Des Moines DSM to San Diego SAN at the right price  

Airfares to San Diego SAN from Des Moines DSM currently cost between $138 and $232. It’s usually cheaper to book a round trip than two separate one-way flights. Prices and availability subject to change. Additional terms may apply. 

 

Book one-way flights from Des Moines DSM to San Diego SAN 

If you want to be flexible about when you return, or keep your travel options open ended, a one-way flight could be just the ticket! You’ll find one-way airfares from Des Moines DSM to San Diego SAN on Travelocity starting at $59. Prices and availability subject to change. Additional terms may apply. 

 

Get to San Diego SAN from Des Moines DSM quicker with direct flights. 

Get to San Diego faster, without the hassle of changing planes and moving baggage, by booking a direct flight. Expect your direct flight to SAN from DSM to take around hour(s) min(s).  

 

Find our cheapest airfares for flights from Des Moines DSM to San Diego SAN

Find cheap flight deals by using our search filters to sort results starting with the lowest price airfares to SAN from DSM. Our Price Match Promise means if you find a lower rate on Travelocity.com or on another US-based website within 24 hours of booking, we’ll credit or refund the difference.  

 

Get our best airfare deals for your flight from Des Moines DSM to San Diego SAN today 

If you’re flexible about when you travel, December is usually the cheapest month to fly from Des Moines DSM to San Diego SAN. If you need to be more specific, search by date and arrival and departure times.Then, compare prices across different airlines, and sort results by lowest price first. 

 

Book flexible airline tickets for flights to San Diego SAN from Des Moines DSM 

Some airlines let you change your travel dates without charging a fee. Use our ‘no change fee’ filter to see which flights to SAN from DSM have this option.  

 

Travel with confidence when you book flights to San Diego SAN from Des Moines DSM with Travelocity 

We’ve secured fantastic deals with all the main airline carriers and it’s easy to compare, choose, and book with Travelocity. With 24/7 customer service and our free 'App', we’ll always keep you moving. 

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.