American Airlines Flight 4506 Deals & Information (2025/2026)

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American Airlines Flight 4506 Route Deals From $158

The cheapest prices found with in the last 7 days for return flights were $295 and $158 for one-way flights to Columbia Metropolitan for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Mar 1 - Wed, Mar 5
LGA
LaGuardia
CAE
Columbia Metropolitan
$295 Roundtrip, found 12 hours ago
$295
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Mar 1 from LaGuardia to Columbia Metropolitan, returning Wed, Mar 5, priced at $295 found 12 hours ago
Sat, Mar 1 - Wed, Mar 5
LGA
LaGuardia
CAE
Columbia Metropolitan
$305 Roundtrip, found 12 hours ago
$305
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Mar 1 from LaGuardia to Columbia Metropolitan, returning Wed, Mar 5, priced at $305 found 12 hours ago
Wed, Mar 5 - Sat, Mar 8
LGA
LaGuardia
CAE
Columbia Metropolitan
$305 Roundtrip, found 13 hours ago
$305
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Mar 5 from LaGuardia to Columbia Metropolitan, returning Sat, Mar 8, priced at $305 found 13 hours ago
Wed, Mar 5 - Sat, Mar 8
LGA
LaGuardia
CAE
Columbia Metropolitan
$319 Roundtrip, found 13 hours ago
$319
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Mar 5 from LaGuardia to Columbia Metropolitan, returning Sat, Mar 8, priced at $319 found 13 hours ago
Sat, Mar 1 - Wed, Mar 5
LGA
LaGuardia
CAE
Columbia Metropolitan
$325 Roundtrip, found 12 hours ago
$325
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Mar 1 from LaGuardia to Columbia Metropolitan, returning Wed, Mar 5, priced at $325 found 12 hours ago
Wed, Mar 5 - Sat, Mar 8
LGA
LaGuardia
CAE
Columbia Metropolitan
$329 Roundtrip, found 13 hours ago
$329
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Mar 5 from LaGuardia to Columbia Metropolitan, returning Sat, Mar 8, priced at $329 found 13 hours ago
Wed, Mar 5 - Sat, Mar 8
LGA
LaGuardia
CAE
Columbia Metropolitan
$329 Roundtrip, found 13 hours ago
$329
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Mar 5 from LaGuardia to Columbia Metropolitan, returning Sat, Mar 8, priced at $329 found 13 hours ago
Wed, Mar 5 - Sat, Mar 8
LGA
LaGuardia
CAE
Columbia Metropolitan
$334 Roundtrip, found 13 hours ago
$334
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Mar 5 from LaGuardia to Columbia Metropolitan, returning Sat, Mar 8, priced at $334 found 13 hours ago
Sat, Mar 1 - Wed, Mar 5
LGA
LaGuardia
CAE
Columbia Metropolitan
$335 Roundtrip, found 12 hours ago
$335
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Mar 1 from LaGuardia to Columbia Metropolitan, returning Wed, Mar 5, priced at $335 found 12 hours ago
Fri, May 16 - Sat, May 17
LGA
LaGuardia
CAE
Columbia Metropolitan
$337 Roundtrip, found 1 day ago
$337
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, May 16 from LaGuardia to Columbia Metropolitan, returning Sat, May 17, priced at $337 found 1 day ago

Frequently asked questions

What route does flight number AA4506 take?
AA4506 serves multiple routes, but the most common is between Nashville International Airport and Raleigh, NC Airport (RDU-Raleigh - Durham Intl.). If on a non-stop flight, you’ll disembark the plane in roughly 1 hour and 34 minutes. Multi-stop flights can also operate under the same number, as can services on other routes.
What kind of plane is on flight number AA4506?
AA4506 is a flight number that’s used on many different routes. If you’re booked on its most popular route, Nashville International Airport to Raleigh–Durham Airport, chances are you’ll be boarding the Embraer 175.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4506 flight with Travelocity, please visit our Customer Service Portal.