
$100 Cheap American Airlines flights from Knoxville to Columbus (TYS to CMH)
Find The Best Day To Fly from Knoxville to Columbus
Amazing American Airlines TYS to CMH Flight Deals
The cheapest flights to John Glenn Columbus Intl. found within the past 7 days were $227 round trip and $100 one way. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover our best American Airlines flight from Knoxville TYS to Columbus CMH
To find the best deals on flights to Knoxville from Columbus with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from Knoxville TYS to Columbus CMH with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $227 to $313, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from Knoxville TYS to Columbus CMH
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Knoxville to Columbus costs from $100. Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to Columbus CMH from Knoxville TYS with American Airlines
To find a cheap American Airlines flight from Knoxville TYS to Columbus CMH, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from Knoxville TYS to Columbus CMH
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as May, or if you book a flight with a stopover.
Find nonstop flights from Knoxville TYS to Columbus CMH with American Airlines
If you’re keen to be on Columbus soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from Knoxville TYS to Columbus CMH
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to Columbus CMH from Knoxville TYS with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
Travelers ❤️ these 🏨 after their flight to Columbus

Reviewed on Apr 23, 2025

Reviewed on Apr 23, 2025

Reviewed on Apr 23, 2025
Popular American Airlines Flight Routes from TYS
Top American Airlines Flight Routes from CMH
- American Airlines CMH to SEA
- American Airlines CMH to LAS
- American Airlines CMH to FLL
- American Airlines CMH to BOS
- American Airlines CMH to DCA
- American Airlines CMH to MIA
- American Airlines CMH to IAH
- American Airlines CMH to HOU
- American Airlines CMH to AUS
- American Airlines CMH to LGA
- American Airlines CMH to LAX
Top Flights for American Airlines originating from TYS
Domestic
- Newark Liberty Intl. Airport to Miami (EWR - MIA)
- New York to Montego Bay (JFK - MBJ)
- New York to Santiago (JFK - STI)
- New York to San Juan (JFK - SJU)
- New York to Orlando (LGA - MCO)
- Newark Liberty Intl. Airport to Las Vegas (EWR - LAS)
- San Juan to Orlando (SJU - MCO)
- Newark Liberty Intl. Airport to Fort Lauderdale (EWR - FLL)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Los Angeles to Tokyo (LAX - NRT)
International
- Lisbon to Toronto (LIS - YYZ)
- Newark Liberty Intl. Airport to Miami (EWR - MIA)
- San Juan to Orlando (SJU - MCO)
- Los Angeles to San Salvador (LAX - SAL)
- Los Angeles to Tokyo (LAX - HND)
- Chicago to Orlando (ORD - MCO)
- Orlando to San Juan (MCO - SJU)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- New York to San Juan (JFK - SJU)
- Newark Liberty Intl. Airport to Las Vegas (EWR - LAS)