Southern Minnesota Vacation Packages 2025 from $248

Southern Minnesota flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Cambria Hotel Minneapolis Downtown

Downtown Minneapolis

per person

Mar 6 - Mar 9

found 4 hours ago

Roundtrip flight included

Detroit (DTW) to Minneapolis (MSP)

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Self parking, a snack bar/deli, and dry cleaning are also offered.

Emery, Autograph Collection Hotel

Downtown Minneapolis

per person

Apr 18 - Apr 21

found 3 hours ago

Roundtrip flight included

Detroit (DTW) to Minneapolis (MSP)

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and valet parking. Self parking, a coffee shop, and a garden are also offered.

MOXY Minneapolis Uptown

Calhoun Isles

per person

Apr 18 - Apr 21

found 3 hours ago

Roundtrip flight included

Detroit (DTW) to Minneapolis (MSP)

This hotel features a gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. A snack bar/deli, a grocery/convenience store, and a library are also on offer.

Hyatt Centric Downtown Minneapolis

Downtown Minneapolis

per person

Mar 6 - Mar 9

found 4 hours ago

Roundtrip flight included

Detroit (DTW) to Minneapolis (MSP)

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Limo/town car service, express check-out, and dry cleaning are also on offer.

The Marquette Hotel, Curio Collection by Hilton

Downtown Minneapolis

per person

Mar 6 - Mar 9

found 4 hours ago

Roundtrip flight included

Detroit (DTW) to Minneapolis (MSP)

This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Self parking, express check-in, and express check-out are also offered.

Top Southern Minnesota hotels deals

Kahler Grand Hotel

20 2nd Ave Sw, Rochester, MN

Free Cancellation

Reserve now, pay when you stay

$156

includes taxes & fees

$135 per night

Feb 8 - Feb 9

This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. You'll appreciate the spa tub, bar/lounge, and laundry facilities.

Pool

Hot Tub

Kahler Inn and Suites - Mayo Clinic Area

9 3rd Ave Nw, Rochester, MN

Free Cancellation

Reserve now, pay when you stay

$140

includes taxes & fees

$121 per night

Feb 10 - Feb 11

This hotel features a restaurant, an indoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Enjoy the gym and free self-serve breakfast each morning.

AmericInn by Wyndham Rochester Near Mayo Clinic

1625 Broadway Ave S, Rochester, MN

Free Cancellation

Reserve now, pay when you stay

$85

includes taxes & fees

$74 per night

Jan 30 - Jan 31

This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the free WiFi in public areas and onsite conference space. Enjoy the spa tub and free perks like continental breakfast and free self parking.

Pool

Hot Tub

Hyatt House Rochester/Mayo Clinic Area

110 Civic Center Drive NW, Rochester, MN

Free Cancellation

Reserve now, pay when you stay

$131

includes taxes & fees

$114 per night

Feb 14 - Feb 15

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the spa tub and free perks like buffet breakfast and an area shuttle.

Pool

Hot Tub

EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel

101 11TH Avenue SW, Suite A, Rochester, MN

Free Cancellation

$121

includes taxes & fees

$105 per night

Feb 7 - Feb 8

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the gym and perks like a free area shuttle.

Pool

Hot Tub

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw, Rochester, MN

Free Cancellation

Reserve now, pay when you stay

$92

includes taxes & fees

$80 per night

Jan 28 - Jan 29

2 indoor pools, a 24-hour gym, and a spa tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly dining. Enjoy a meal from the restaurant and perks like free full breakfast and free self parking.

Pool

Hot Tub

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Winona State University

4.5/5(94 reviews)

Enjoy the collegiate vibe when you visit Winona State University, during your trip to Winona. Stroll along the riverfront or experience the area's museums.

Hard to beat the sunsets on Lake Shetek, my second home ❤️

Lake Shetek State Park

4.5/5(5 reviews)

Explore the great outdoors at Lake Shetek State Park, a lovely green space in The Lakes. Take in the museums while you're in the area.

Mayo Clinic

5/5(1,146 reviews)

Though Mayo Clinic might be what brings you to town, perhaps you'll have a chance to explore more of Rochester while you are here.

Frequently asked questions

How much are vacation packages to Southern Minnesota?

You’ll be surprised — you can unwind in Southern Minnesota for a mere $248. Allow Travelocity to save you money and hassle with our excellent vacation packages. With experiences, hotels and flights all ready to go, why wait any longer?

Where can I get the best vacation package deals for Southern Minnesota?

It’s simple — browse Travelocity. With no less than 400 airlines and 1,000,000 properties worldwide, it’s a breeze to put together a Southern Minnesota package deal that fits your budget.

Why should I book my Southern Minnesota vacation package via Travelocity?

By booking your hotel, flights, activities and car rental all in the one place, you’ll save both time and money. All our bookings come with an expert team of customer service specialists available 24/7, and you’ll know that you’ll always score the best deal possible with our Price Match Guarantee. So, what are you waiting for? Book the getaway of your dreams today and get packing!

Can I save on my Southern Minnesota car rental if I book it with my hotel or flight?

Sure can. And our Southern Minnesota vacation packages are the perfect way to do it. In just a few clicks you can save money and time by combining your bookings. Collect the keys to your rental car and feel the freedom of the open road. Looking for things to do? Add a few tours to your package and make savings on those too.

What is there to do in Southern Minnesota?

A vibrant and attractive destination, Southern Minnesota boasts some incredible tourist attractions. Treasure Island Casino and Mayo Civic Center are two of the local highlights.