Explore 16 Luxury Hotels in Southern Maryland

Name: Colony South Hotel & Conference Center
Rating: 6.4

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Best Luxury Hotels in Southern Maryland

Gaylord National Resort & Convention Center

201 Waterfront Street, Fort Washington, MD

Fully refundableReserve now, pay when you stay

$357

includes taxes & fees

$303 per night

May 18 - May 19

This smoke-free resort features a full-service spa, a marina, and 3 restaurants. Traveling on business? Take advantage of the business center, express check-in, ...

8.6/10 Excellent! (1,003 reviews)

"I loved this property! It was exceptional. We enjoyed the spaciousness of the Atrium and many good options for food and entertainment. My only note is the lifeguard at the pool was inattentive. She was on her phone."

Reviewed on Apr 25, 2025

Hampton Inn Waldorf

3750 Crain Hwy, Waldorf, MD

Fully refundableReserve now, pay when you stay

$122

includes taxes & fees

$110 per night

May 4 - May 5

This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests ...

8.6/10 Excellent! (1,002 reviews)

"Many food options around the area..."

Reviewed on Apr 24, 2025

Springhill Suites by Marriott Prince Frederick

75 Sherry Lane, Prince Frederick, MD

Fully refundableReserve now, pay when you stay

$149

includes taxes & fees

$134 per night

May 5 - May 6

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...

8.4/10 Very Good! (870 reviews)

4 out of 5 Stars

"Bathroom soap dispenser was empty and light in bathroom kept flickering. I think that needs checked out. Buffet was so-so. Regular coffee was out both days we tried to use it and it was still early on the breakfast timetable."

Reviewed on Apr 21, 2025

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Country Inn & Suites by Radisson, Camp Springs (Andrews Air Force Base), MD

4950 Mercedes Blvd, Suitland, MD

Fully refundable

$147

includes taxes & fees

$131 per night

May 1 - May 2

A restaurant and a gym are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free ...

8.4/10 Very Good! (1,001 reviews)

Great Place

"We stayed for 5 nights and everything was excellent. Staff was polite and friendly. Will definitely stay again."

Reviewed on Apr 22, 2025

Holiday Inn Express Washington DC East - Andrews AFB by IHG

5001 Mercedes Blvd, Suitland, MD

Fully refundable

$132

includes taxes & fees

$117 per night

May 1 - May 2

This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free ...

8/10 Very Good! (1,000 reviews)

"The hotel room was very nice. The desk manager was friendly, but hard to understand. Carpets in the rooms and hallways are very stained. Need to replace."

Reviewed on Apr 13, 2025

La Quinta Inn by Wyndham Waldorf

11770 Business Park Dr, Waldorf, MD

Fully refundableReserve now, pay when you stay

$93

includes taxes & fees

$84 per night

May 4 - May 5

This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...

7.4/10 Good! (999 reviews)

"The room very nice. The receptionist was very nice. It smelled nice. Very nice size room."

Reviewed on Apr 7, 2025

Red Carpet Inn Indian Head

4696 Indian Head Hwy, Indian Head, MD

Fully refundableReserve now, pay when you stay

$79

includes taxes & fees

$71 per night

Apr 28 - Apr 29

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the laundry service. The front ...

7.2/10 Good! (545 reviews)

"good"

Reviewed on Feb 25, 2025

Colony South Hotel & Conference Center

7401 Surratts Road, Clinton, MD

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling for business? Take advantage of the business center, laundry service, and conference ...

6.4/10 (998 reviews)

"Throughly cleaning is needed in the rooms. Bathrooms weren’t cleaned."

Reviewed on Jun 24, 2020

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

5 star hotels in Southern Maryland

Swanendele Inn at St. Mary's Maryland

49946 Airedele Rd, Ridge, MD

$309

includes taxes & fees

$278 per night

May 5 - May 6

10/10 Exceptional! (25 reviews)

Southern Maryland Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Southern Maryland luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Southern Maryland to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Southern Maryland will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Southern Maryland, and plan your next opulent escape.

Southern Maryland hotels essential information

Accommodation	652 hotels
Lowest Price	$79
Highest Price	$361
Popular hotels	Colony South Hotel & Conference Center, Springhill Suites by Marriott Prince Frederick, Gaylord National Resort & Convention Center, Hampton Inn Waldorf, La Quinta Inn by Wyndham Waldorf, Country Inn & Suites by Radisson, Camp Springs (Andrews Air Force Base), MD, Red Carpet Inn Indian Head, Holiday Inn Express Washington DC East - Andrews AFB by IHG

Popular Luxury Stays in Southern Maryland

5 Stars Luxury stays in Southern Maryland

Luxury stays in Southern Maryland with spa

Popular places to visit

George Washington's Mount Vernon

4.5/5(167 reviews)

Gain fascinating insights into the life of America’s first president at this beautifully restored country estate set on the shores of the Potomac River.