Book a hotel near Santee National Wildlife Refuge, Summerton
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Top hotels close to Santee National Wildlife Refuge

Executive 2 BR/2 BA Lakefront Corner Suite Condo
3.04 mi from Santee National Wildlife Refuge
An outdoor pool is featured at this condo, along with a garden and laundry facilities. Barbecue grills are provided for your convenience.
Pool
Kitchen

Sunsets on Lake Marion
3.38 mi from Santee National Wildlife Refuge
This condo features laundry facilities.
Washer
Dryer

Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
3.66 mi from Santee National Wildlife Refuge
A gym is featured at this vacation home, along with a garden and laundry facilities. Families will appreciate the arcade/game room and barbecue grills.
Kitchen
Washer

Quality Inn & Suites
8929 Old Number Six Highway, Santee, SC
Free Cancellation
Reserve now, pay when you stay
4.26 mi from Santee National Wildlife Refuge
The price is $70 per night
$70
includes taxes & fees
$64 per night
May 5 - May 6
This hotel features 7 restaurants and a seasonal outdoor pool. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink at the bar/lounge and enjoy free perks like full breakfast and free self parking.
Pool
Breakfast included

Hampton Inn Santee-I-95
9060 Old Number Six Hwy, Santee, SC
Free Cancellation
Reserve now, pay when you stay
4.36 mi from Santee National Wildlife Refuge
The price is $158 per night
$158
includes taxes & fees
$143 per night
May 26 - May 27
This hotel features a 24-hour gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. A 24-hour business center, a terrace, and laundry facilities are also on offer.
Pool
Breakfast included

Best Western Plus Santee Inn
I 95 Exit 98, Santee, SC
4.36 mi from Santee National Wildlife Refuge
The price is $127 per night
$127
includes taxes & fees
$115 per night
May 11 - May 12
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.
Pool
Breakfast included

Fairfield Inn & Suites by Marriott Santee
9074 Old Number Six Hwy, Santee, SC
4.36 mi from Santee National Wildlife Refuge
The price is $159 per night
$159
includes taxes & fees
$143 per night
May 5 - May 6
This hotel features an outdoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business center, a snack bar/deli, and a picnic area are also on offer.
Pool
Breakfast included

Travelodge by Wyndham Santee
9117 Old Number Six Hwy, Santee, SC
Free Cancellation
Reserve now, pay when you stay
4.38 mi from Santee National Wildlife Refuge
The price is $68 per night
$68
includes taxes & fees
$61 per night
May 11 - May 12
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A safe deposit box is also provided.
Breakfast included
Pet friendly

Tru By Hilton Santee
263 Britain St. and 273 Britain St., Santee, SC
Free Cancellation
Reserve now, pay when you stay
4.44 mi from Santee National Wildlife Refuge
The price is $122 per night
$122
includes taxes & fees
$110 per night
May 18 - May 19
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide around-the-clock assistance.
Pool
Breakfast included

Holiday Inn Santee by IHG
139 Bradford Blvd, Santee, SC
Free Cancellation
4.45 mi from Santee National Wildlife Refuge
The price is $150 per night
$150
includes taxes & fees
$135 per night
May 27 - May 28
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and perks like free self parking.
Pool
Pet friendly

Baymont by Wyndham Santee
249 Britain Street, Santee, SC
Free Cancellation
Reserve now, pay when you stay
4.48 mi from Santee National Wildlife Refuge
The price is $89 per night
$89
includes taxes & fees
$80 per night
Apr 29 - Apr 30
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the express check-in and free internet in public areas. There's express check-out and multilingual staff can provide around-the-clock assistance.
Breakfast included
Pet friendly

Comfort Inn & Suites Santee
221 Britain St, Santee, SC
Free Cancellation
Reserve now, pay when you stay
4.49 mi from Santee National Wildlife Refuge
The price is $122 per night
$122
includes taxes & fees
$110 per night
May 11 - May 12
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business center, a lobby fireplace, and laundry facilities are also on offer.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in Santee National Wildlife Refuge
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Santee National Wildlife Refuge hotels essential information
Accommodation | 343 hotels |
---|---|
Lowest Price | $68 |
Highest Price | $159 |
Popular hotels | Baymont by Wyndham Santee, Tru By Hilton Santee, Fairfield Inn & Suites by Marriott Santee, Holiday Inn Santee by IHG, Hampton Inn Santee-I-95, Best Western Plus Santee Inn, Comfort Inn & Suites Santee, Quality Inn & Suites, Executive 2 BR/2 BA Lakefront Corner Suite Condo, Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS, Travelodge by Wyndham Santee, Sunsets on Lake Marion |
Recent Santee National Wildlife Refuge hotel reviews by fellow wanderers

Fairfield Inn & Suites by Marriott Santee
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Very clean property. Seemed like it was just built. Parking was safe and easy. Breakfast buffet was delicious and hot. Staff friendly ."
A verified traveler stayed at Fairfield Inn & Suites by Marriott Santee
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