Find & compare luxury hotels in Mission Valley, San Diego

Name: Wyndham San Diego Bayside
Price range: $181

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Best Luxury Hotels in Mission Valley

San Diego Marriott Gaslamp Quarter

660 K St, San Diego, CA

Free Cancellation

Reserve now, pay when you stay

$191

includes taxes & fees

$169 per night

Feb 23 - Feb 24

A nightclub, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. Express check-out, a computer station, and dry cleaning are also on offer.

Restaurant

Air conditioning

Hyatt Regency Mission Bay Spa and Marina

1441 Quivira Rd, San Diego, CA

Free Cancellation

Reserve now, pay when you stay

$234

includes taxes & fees

$208 per night

Feb 23 - Feb 24

This smoke-free hotel features a full-service spa, a marina, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the 3 outdoor pools and gym, and unwind with a drink at the bar/lounge.

Pool

Hot Tub

Sheraton San Diego Resort

1380 Harbor Island Dr, San Diego, CA

Free Cancellation

Reserve now, pay when you stay

$231

includes taxes & fees

$205 per night

Mar 14 - Mar 15

A marina, 5 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, express check-in, and free airport shuttle. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside bar.

Pool

Hot Tub

Omni San Diego Hotel

675 L St, San Diego, CA

Free Cancellation

Reserve now, pay when you stay

$241

includes taxes & fees

$214 per night

Mar 15 - Mar 16

This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a 24-hour gym on site, and a 24-hour front desk and a coffee shop are also provided.

Manchester Grand Hyatt San Diego

1 Market Pl, San Diego, CA

$261

includes taxes & fees

$231 per night

Mar 6 - Mar 7

This eco-certified hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the hot tub and visit the 3 bars/lounges and poolside bar for drinks.

Pool

Hot Tub

San Diego Marriott La Jolla

4240 La Jolla Village Dr, La Jolla, CA

Free Cancellation

Reserve now, pay when you stay

$162

includes taxes & fees

$143 per night

Feb 28 - Mar 1

This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, express check-out, and valet parking. A bar/lounge, a 24-hour front desk, and a coffee shop are also provided.

Pool

Pet friendly

Hotel Indigo San Diego-Gaslamp Quarter, an IHG Hotel

509 9th Ave, San Diego, CA

Free Cancellation

$249

includes taxes & fees

$221 per night

Feb 23 - Feb 24

This smoke-free hotel's 2 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. A coffee shop, a snack bar/deli, and a grocery/convenience store are also on offer.

Pet friendly

Free WiFi

Loews Coronado Bay Resort

4000 Coronado Bay Rd, Coronado, CA

Free Cancellation

Reserve now, pay when you stay

$278

includes taxes & fees

$250 per night

Feb 23 - Feb 24

A full-service spa, a marina, and 3 outdoor pools are all featured at this hotel. Take the free beach shuttle and relax with sun loungers and beach umbrellas. There's fun for all ages with a children's pool and a playground, and families will appreciate the onsite laundry facilities.

Pool

Hot Tub

Wyndham San Diego Bayside

1355 N Harbor Drive, San Diego, CA

Free Cancellation

Reserve now, pay when you stay

$181

includes taxes & fees

$161 per night

Mar 16 - Mar 17

This smoke-free hotel includes 2 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, express check-out, and free airport shuttle. There's a bar/lounge on site, and concierge services and free newspapers are also provided.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Mission Valley

Marriott Marquis San Diego Marina

333 W Harbor Dr, San Diego, CA

$242

includes taxes & fees

$218 per night

Mar 3 - Mar 4

9/10 Wonderful! (1,614 reviews)

5 star hotels in Mission Valley

Fairmont Grand Del Mar

5300 Grand Del Mar Court, San Diego, CA

$704

includes taxes & fees

$625 per night

Mar 14 - Mar 15

9.4/10 Exceptional! (823 reviews)

Mission Valley Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Mission Valley luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Mission Valley to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Mission Valley will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Mission Valley, and plan your next opulent escape.

Mission Valley hotels essential information

Accommodation	8,454 hotels
Lowest Price	$141
Highest Price	$704
Popular hotels	San Diego Marriott Gaslamp Quarter, Hyatt Regency Mission Bay Spa and Marina, Sheraton San Diego Resort, Omni San Diego Hotel, Manchester Grand Hyatt San Diego, San Diego Marriott La Jolla, Hotel Indigo San Diego-Gaslamp Quarter, an IHG Hotel, Loews Coronado Bay Resort, Wyndham San Diego Bayside