Find & compare luxury hotels in Mission Valley, San Diego

Name: Lafayette Hotel & Club
Price range: $232

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Best Luxury Hotels in Mission Valley

Manchester Grand Hyatt San Diego

1 Market Pl, San Diego, CA

Free Cancellation

Reserve now, pay when you stay

$238

includes taxes & fees

$211 per night

Dec 23 - Dec 24

This eco-certified hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. There's a poolside bar on site, and laundry facilities and concierge services are also provided.

Pool

Pet friendly

Paradise Point Resort & Spa

1404 Vacation Rd, San Diego, CA

Free Cancellation

Reserve now, pay when you stay

$251

includes taxes & fees

$223 per night

Dec 30 - Dec 31

This smoke-free resort features a full-service spa, a marina, and 3 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with kayaking. Enjoy the 5 outdoor pools and perks like free WiFi.

Pool

Hot Tub

Sheraton Mission Valley San Diego Hotel

1433 Camino Del Rio S, San Diego, CA

Free Cancellation

Reserve now, pay when you stay

$141

includes taxes & fees

$125 per night

Dec 29 - Dec 30

This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a spa tub on site, and a 24-hour front desk and a terrace are also provided.

Pool

Hot Tub

San Diego Marriott La Jolla

4240 La Jolla Village Dr, La Jolla, CA

Free Cancellation

Reserve now, pay when you stay

$162

includes taxes & fees

$143 per night

Dec 24 - Dec 25

This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, express check-out, and valet parking. A bar/lounge, a 24-hour front desk, and a coffee shop are also provided.

Hotel Indigo San Diego-Gaslamp Quarter, an IHG Hotel

509 9th Ave, San Diego, CA

Free Cancellation

$184

includes taxes & fees

$163 per night

Dec 23 - Dec 24

This smoke-free hotel's 2 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. A coffee shop, a snack bar/deli, and a grocery/convenience store are also on offer.

Sheraton San Diego Hotel and Marina

1380 Harbor Island Dr, San Diego, CA

Free Cancellation

Reserve now, pay when you stay

$163

includes taxes & fees

$145 per night

Dec 29 - Dec 30

A marina, 6 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center, express check-in, and free airport shuttle. You'll find 2 coffee shops/cafes and 2 spa tubs on site, along with a poolside bar to unwind.

Wyndham San Diego Bayside

1355 N Harbor Drive, San Diego, CA

Free Cancellation

Reserve now, pay when you stay

$171

includes taxes & fees

$152 per night

Jan 1 - Jan 2, 2025

This smoke-free hotel includes 2 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, express check-out, and free airport shuttle. There's a bar/lounge on site, and concierge services and free newspapers are also provided.

Pool

Free airport shuttle

Loews Coronado Bay Resort

4000 Coronado Bay Rd, Coronado, CA

Free Cancellation

Reserve now, pay when you stay

$244

includes taxes & fees

$219 per night

Dec 23 - Dec 24

A full-service spa, a marina, and 3 outdoor pools are all featured at this hotel. Take the free beach shuttle and relax with sun loungers and beach umbrellas. There's fun for all ages with a children's pool and a playground, and families will appreciate the onsite laundry facilities.

Lafayette Hotel & Club

2223 El Cajon Blvd, San Diego, CA

Free Cancellation

Reserve now, pay when you stay

$232

includes taxes & fees

$206 per night

Dec 23 - Dec 24

This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the outdoor pool and conveniences like a 24-hour front desk and concierge services.

Pool

Pet friendly

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Mission Valley

Marriott Marquis San Diego Marina

333 W Harbor Dr, San Diego, CA

$230

includes taxes & fees

$208 per night

Jan 5 - Jan 6, 2025

9/10 Wonderful! (1,619 reviews)

5 star hotels in Mission Valley

Fairmont Grand Del Mar

5300 Grand Del Mar Court, San Diego, CA

$743

includes taxes & fees

$659 per night

Dec 23 - Dec 24

9.4/10 Exceptional! (792 reviews)

Mission Valley Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Mission Valley luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Mission Valley to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Mission Valley will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Mission Valley, and plan your next opulent escape.

Mission Valley hotels essential information

Accommodation	8,296 hotels
Lowest Price	$141
Highest Price	$743
Popular hotels	Manchester Grand Hyatt San Diego, Paradise Point Resort & Spa, Sheraton Mission Valley San Diego Hotel, San Diego Marriott La Jolla, Hotel Indigo San Diego-Gaslamp Quarter, an IHG Hotel, Sheraton San Diego Hotel and Marina, Wyndham San Diego Bayside, Loews Coronado Bay Resort, Lafayette Hotel & Club

Recent Mission Valley Hotel Reviews By Fellow Wanderers

Kings Inn San Diego

5 out of 5

Posted 2 days ago

Travelocity Verified Review

"This is the second time I have stayed here. Highly recommend. I stayed on the second floor this time. Room was very clean and bed was comfortable. Wasn't loud ever, even when staying right near the stairwell. All staff I encountered, were lovely. Parking is at $15 a day, but if you choose to do so, they'll just use the deposit made at check-in towards it at the end of your stay. Definitely will come back."

A verified traveler stayed at Kings Inn San Diego